Hello Manisha, I can understand your concern regarding incorporating traditionally used methods for vaccination. But the use of prefilled, single use syringes has become popular because it is easy, efficient, safer and more hygienic. If we incorporate the use of multi dose vials, it will essentially become like a general purpose syringe. The single use feature will be lost as you will have to fill the syringe from the vial and then inject it. Another advantage of the prefilled syringe is that it is faster and easier to use. That would also be lost if the concept is used with multi dose vials. Due to the inherent advantages of prefilled syringes, use of multi dose vials is rapidly reducing. Also, the manufacturing process of blow-fill-seal is efficient only with prefilled syringes. Currently this is at an idea stage so it is difficult to test it. But we can get reviews from doctors or physicians if that helps. Thanks
Hi Isaac, Thanks for your interest. Currently, needle covers on injections are removable. So they are thrown away as soon as they are taken off the injection. After injecting, needles (at immunisation camps) are put in a special container/dustbin immediately after use. But this poses a serious threat to people who handle this waste i.e. cleaning, sanitation and recycling personnel as they might come in direct contact with the exposed needles. In home use scenario, it is even more precarious as kids are involved and there is not fixed method of disposal. For this reason, Ekject has a built in top cap that can be used to cover the needle after use and before disposal. Ekject will be directly available at local pharmacies, Public health clinics in urban areas. So they would be easily accessible to caregivers. They can purchase the prefilled syringe and store it at home in a refrigerator till they can use it. I believe the best way spark a change in people's mindsets is to have testimonials of caregivers who are already vaccinating their kids themselves. Since vaccines are intramuscular injections they can be applied to a general muscle group without much training. This is where testimonials would help. To make caregivers feel confident that no special skill is required to administer the vaccines.
Thank you for sharing Amy's idea. It definitely overlaps in term of the scenario of usage as it would assist caregivers and pacify kids while administering the vaccine.
This could be a good reference. https://pharmaceuticalcommerce.com/manufacturing-and-packaging/a-growing-preference-for-ready-to-administer-vaccines-new-guidelines-evidence-and-trends/
You are right. What you are referring to are multi dose vials. They have dried drug in an ampule which is mixed with saline using a syringe and mixed. The same syringe is used to draw the liquid drug and inject. Due to safety, efficiency and skill related issues of the multi dose vials, since 2012, organisations like CDC are actively promoting prefilled syringes for vaccination.
The prefilled syringe is a replacement to the multi dose vials that Ashley is talking about. Multi dose vials were used in mass vaccination programmes as they need less storage space (as they are dry) but take more time, effort and skill to administer and are prone to safety hazards like needle pricks and reuse.
From my personal experience, our physician himself suggested my mother prefilled syringes as she wanted to vaccinate us herself since she was concerned about safety at public vaccination events.